Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323

Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323 Potent cyclic urea HIV protease inhibitors with benzofused heterocycles as P2/P2′ groups A bis-[N-3-(1-hydroxy-1-methyl-ethyl)-benzyl)-cyclic urea as a HIV protease inhibitor The synthesis and evaluation of cyclic ureas as HIV protease inhibitors: Modifications of the P1/P1′ residues Synthesis of PotentC₂-Symmetric, Diol-Based HIV-1 Protease Inhibitors. Investigation of Thioalkyl and Thioaryl P1/P1‘ Substituents Design and synthesis of potent HIV-1 protease inhibitors incorporating hydroxyprolinamides as novel P2 ligands Novel pseudosymmetric inhibitors of HIV-1 protease Design of HIV-1 Protease Inhibitors with C3-Substituted Hexahydrocyclopentafuranyl Urethanes as P2-Ligands: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Structure Novel inhibitors of HIV protease Cyclic HIV Protease Inhibitors:  Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas