Novel inhibitors of HIV protease

Novel inhibitors of HIV protease Synthesis of novel HIV protease inhibitors (PI) with activity against PI-resistant virus Design of HIV-1 Protease Inhibitors with Pyrrolidinones and Oxazolidinones as Novel P1′-Ligands To Enhance Backbone-Binding Interactions with Protease: Synthesis, Biological Evaluation, and Protein−Ligand X-ray Studies Potent inhibitors of the HIV-1 protease incorporating cyclic urea P1–P2 scaffold Design and synthesis of potent HIV-1 protease inhibitors incorporating hydroxyprolinamides as novel P2 ligands The synthesis and evaluation of cyclic ureas as HIV protease inhibitors: Modifications of the P1/P1′ residues Novel P1 chain-extended HIV protease inhibitors possessing potent anti-HIV activity and remarkable inverse antiviral resistance profiles Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2′ side chains P1′ oxadiazole protease inhibitors with excellent activity against native and protease inhibitor-resistant HIV-1