C32-amino derivatives of the immunosuppressant ascomycin

C32-amino derivatives of the immunosuppressant ascomycin Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity C32-O-imidazol-2-yl-methyl ether derivatives of the immunosuppressant ascomycin with improved therapeutic potential Preparation and immunosuppressive activity of 32-(O)-acylated and 32-(O)-thioacylated analogues of ascomycin Studies on an immunosuppressive macrolactam, ascomycin: Synthesis of a C-33 hydroxyl derivative C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study 32-Ascomycinyloxyacetic Acid Derived Immunosuppressants. Independence of Immunophilin Binding and Immunosuppressive Potency Alkyl ether derivatives of the FK-506 related, immunosuppressive macrolide L-683,742 (C31-O-desmethyl ascomycin) Alkyl ether analogs of the FK-506 related, immunosuppressive macrolide L-683,590 (ascomycin) Retention of Immunosuppressant Activity in an Ascomycin Analogue Lacking a Hydrogen-Bonding Interaction with FKBP12