Alkyl ether derivatives of the FK-506 related, immunosuppressive macrolide L-683,742 (C31-O-desmethyl ascomycin)

Alkyl ether derivatives of the FK-506 related, immunosuppressive macrolide L-683,742 (C31-O-desmethyl ascomycin) Alkyl ether analogs of the FK-506 related, immunosuppressive macrolide L-683,590 (ascomycin) C32-O-imidazol-2-yl-methyl ether derivatives of the immunosuppressant ascomycin with improved therapeutic potential Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity Preparation and in vitro activity of aryl ether derivatives of the FK-506 related immunosuppressive macrolides ascomycin and L-683,742 Studies on an immunosuppressive macrolactam, ascomycin: Synthesis of a C-33 hydroxyl derivative Microbial transformations of immunosuppressive compounds. IV. Hydroxylation and hemiketal formation of ascomycin(immunomycin) by Streptomyces sp. MA6970(ATCC No.55281). Novel derivatives at the C21 position of the FK-506 macrocycle C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study 32-Ascomycinyloxyacetic Acid Derived Immunosuppressants. Independence of Immunophilin Binding and Immunosuppressive Potency