Antifungal rapamycin analogues with reduced immunosuppressive activity

Antifungal rapamycin analogues with reduced immunosuppressive activity Generation of Novel Rapamycin Structures by Microbial Manipulations. Manipulation of the C(22)-C(27) region of rapamycin: Stability issues and biological implications Rapamycin analogs with reduced systemic exposure Cleavage of the cyclohexyl-subunit of rapamycin results in loss of immunosuppressive activity Antifungal lipopeptides: Structure-activity relationships of 3-hydroxyglutamine-modified pneumocandin B0 derivatives Synthesis and Immunosuppressive Activity of 2-Substituted 2-Aminopropane-1,3-diols and 2-Aminoethanols Structure-activity studies of nonmacrocyclic rapamycin derivatives 2-aminoalchohol immunosuppressants: Structure-activity relationships Novel derivatives at the C21 position of the FK-506 macrocycle