The development of new bicyclic pyrazole-based cytokine synthesis inhibitors

The development of new bicyclic pyrazole-based cytokine synthesis inhibitors The development of monocyclic pyrazolone based cytokine synthesis inhibitors Development of Orally Bioavailable Bicyclic Pyrazolones as Inhibitors of Tumor Necrosis Factor-α Production The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-α production From Imidazoles to Pyrimidines:  New Inhibitors of Cytokine Release Synthesis and bioactivities of novel bicyclic thiophenes and 4,5,6,7-tetrahydrothieno[2,3-c]pyridines as inhibitors of tumor necrosis factor-α (TNF-α) production Potent inhibitors of the MAP kinase p38 The development of new triazole based inhibitors of tumor necrosis factor-α (TNF-α) production Pyridinylquinoxalines and Pyridinylpyridopyrazines as Lead Compounds for Novel p38α Mitogen-Activated Protein Kinase Inhibitors Imidazole Inhibitors of Cytokine Release:  Probing Substituents in the 2 Position