5-Fluorinated l-Lysine Analogues as Selective Induced Nitric Oxide Synthase Inhibitors

Journal of Medicinal Chemistry
2004.0

Abstract

5(S)-Fluoro-N6-(iminoethyl)-l-lysine (14), an analogue of the potent, selective induced nitric oxide synthase (iNOS) inhibitor iminoethyl-l-lysine (1), was synthesized and found to be a selective iNOS inhibitor.

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