Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase

Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase Phenothiazine Inhibitors of Trypanothione Reductase as Potential Antitrypanosomal and Antileishmanial Drugs Design, synthesis and biological evaluation of quinazoline derivatives as anti-trypanosomatid and anti-plasmodial agents The structure-based design and synthesis of selective inhibitors of trypanosoma cruzi dihydrofolate reductase Quinol derivatives as potential trypanocidal agents High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity Trypanothione Reductase High-Throughput Screening Campaign Identifies Novel Classes of Inhibitors with Antiparasitic Activity Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine Discovery of a quinoline-based phenyl sulfone derivative as an antitrypanosomal agent Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase