Second generation analogs of rigid 6,7-spiro scaffolds targeting the bacterial ribosome

Second generation analogs of rigid 6,7-spiro scaffolds targeting the bacterial ribosome Rigid spiroethers targeting the decoding center of the bacterial ribosome Effects of 5-O-Ribosylation of Aminoglycosides on Antimicrobial Activity and Selective Perturbation of Bacterial Translation Synthesis and SAR of 3,5-diamino-piperidine derivatives: Novel antibacterial translation inhibitors as aminoglycoside mimetics The use of aminoglycoside derivatives to study the mechanism of aminoglycoside 6′-N-acetyltransferase and the role of 6′-NH2 in antibacterial activity The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes Semisynthetic aminoglycoside antibacterials. 6. Synthesis of sisomicin, antibiotic G-52, and novel 6'-substituted analogs of sisomicin from aminoglycoside 66-40C The synthesis and 16S A-site rRNA recognition of carbohydrate-free aminoglycosides Binding of Aminoglycoside Antibiotics with Modified A-site 16S rRNA Construct Containing Non-Nucleotide Linkers Synthesis of (+),(−)-neamine and their positional isomers as potential antibiotics