Part 1: N-Alkylated glycines as potent α2δ ligands
Bioorganic & Medicinal Chemistry Letters
2011.0
Abstract
A new series of glycine-derived ligands of the α(2)δ subunit of voltage gated calcium channels is described. Several novel compounds (7) based on (6) were prepared that possessed a potency <100 nM in the α(2)δ binding assay.