The present study reports the isolation and structural elucidation of two new glycosides of flavone methyl ethers from the leaves and shoots of Murraya paniculata. Air-dried leaves and shoots of M. paniculata were extracted with 50% ethanol, and the extract was partitioned with petroleum ether, EtOAc, and n-butanol. The n-butanol extract was purified via silica gel column chromatography to obtain compounds 1 and 2. Their structures were determined using HRESI-MS, UV, 1H NMR, 13C NMR, HMQC, and HMBC spectra as 5,8,3'-trihydroxy-6,7,4'-trimethoxy flavone 8-O-β-glucopyranoside (1) and 5,8-dihydroxy-6,7,3',4'-tetramethoxy flavone 8-O-β-glucopyranoside (2). Chemotaxonomic significance analysis showed that these highly methoxylated flavone glycosides are typical of Citreae species but not Clauseneae, suggesting M. paniculata is chemically similar to other Citreae species, supporting its taxonomic placement in Citreae s.l.