1. From the epigeal part of the plant H. perforatum growing in the Dzhungarian Ala-Tau we have isolated the lignane eudesmin, the known alkaloids evoxine, flindersine, and 7-isopentenyloxy-γ-fagarine, and the new alkaloids haplamine, glycoperine, and methylevoxine. It has been shown that haplamine has the structure of 6-methoxyflindersine, glycoperine the structure of 7-hydroxy-4,8-dimethoxyfuranoquinoline 7-O-α-L-rhamnopyranoside, and methylevoxine the structure of 4,8-dimethoxy-7-(2′-hydroxy-3′-methoxy-3′-methylbutoxy)furanoquinoline. © 1977 Plenum Publishing Corporation.