Escholerine (C41H61O13N), a new tetraester of protoverine, as well as neogermitrine and veratroylzygadenine, have been isolated from Veratrum eschscholtzii Gray. On hydrolysis, escholerine yielded the alkamine protoverine, two moles of acetic acid and a mole each of (livo)-α-methylbutyric acid and angelic acid. © 1954, American Chemical Society. All rights reserved.