A chemical investigation of Veratrum fimbriatum Gray has yielded two new hypotensively active germine esters, germanitrine (C39H59O11N), and germinitrine (C39H57011N), as well as neogermitrine, jervine and pseudojervine. In addition, the alkaloidal ester, veratroylzygadenine, previously isolated from Zygadenus venenosus Wats was found to be present in this species of veratrum. On hydrolysis, the triester germanitrine affords germine, acetic acid, tiglic acid and (l)-α-methylbutyric acid. On methanolysis, germanitrine readily loses a labile acetyl group yielding germanidine (C37H57O10N). The hydrolysis of the triester germinitrine, yielded germine, acetic acid, tiglic acid and angelic acid. © 1953, American Chemical Society. All rights reserved.