Indinavir analogues with blocked metabolism sites as HIV protease inhibitors with improved pharmacological profiles and high potency against PI-Resistant viral strains

Indinavir analogues with blocked metabolism sites as HIV protease inhibitors with improved pharmacological profiles and high potency against PI-Resistant viral strains Synthesis and activity of novel HIV protease inhibitors with improved potency against multiple PI-resistant viral strains The design, synthesis and evaluation of novel HIV-1 protease inhibitors with high potency against PI-resistant viral strains Novel HIV-1 protease inhibitors active against multiple PI-Resistant viral strains: coadministration with indinavir A Combinatorial Library of Indinavir Analogues and Its In Vitro and In Vivo Studies HIV-1 protease inhibitors with picomolar potency against PI-resistant HIV-1 by modification of the P1′ substituent HIV protease inhibitors with picomolar potency against PI-Resistant HIV-1 by extension of the P3 substituent Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus Synthesis of novel HIV protease inhibitors (PI) with activity against PI-resistant virus Novel arylsulfonamides possessing sub-picomolar HIV protease activities and potent anti-HIV activity against wild-type and drug-resistant viral strains