Carboxylate bioisosteres of gabapentin

Carboxylate bioisosteres of gabapentin Carboxylate bioisosteres of pregabalin Oxadiazolone bioisosteres of pregabalin and gabapentin Synthesis and in vivo evaluation of 3,4-disubstituted gababutins Structure–activity relationships of α-amino acid ligands for the α2δ subunit of voltage-gated calcium channels Synthesis and biological evaluation of conformationally restricted gabapentin analogues Investigation into the preferred conformation of gabapentin for interaction with its binding site on the α2δ subunit of a calcium channel Hydroxy-1,2,5-oxadiazolyl Moiety as Bioisoster of the Carboxy Function. Synthesis, Ionization Constants, and Pharmacological Characterization of γ-Aminobutyric Acid (GABA) Related Compounds Structure−Activity Relationships of Pregabalin and Analogues That Target the α₂-δ Protein Synthesis and in vivo evaluation of 3-substituted gababutins