Synthesis and in vivo evaluation of 3,4-disubstituted gababutins

Synthesis and in vivo evaluation of 3,4-disubstituted gababutins Synthesis and in vivo evaluation of 3-substituted gababutins Carboxylate bioisosteres of gabapentin Synthesis and biological evaluation of conformationally restricted gabapentin analogues Carboxylate bioisosteres of pregabalin Investigation into the preferred conformation of gabapentin for interaction with its binding site on the α2δ subunit of a calcium channel Structure–activity relationships of α-amino acid ligands for the α2δ subunit of voltage-gated calcium channels Synthesis, biological evaluation and structure–activity relationship of new GABA uptake inhibitors, derivatives of 4-aminobutanamides Synthesis of N-substituted acyclic β-amino acids and their investigation as GABA uptake inhibitors Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury